sRAGE alleviates neutrophilic asthma by blocking HMGB1/RAGE signalling in airway dendritic cells

Receptor for advanced glycation end products (RAGE) plays a role in inflammatory reactions. The soluble form of RAGE (sRAGE) acts as a decoy to inhibit interactions of RAGE with advanced glycation end products such as High mobility group box 1 (HMGB1). We have demonstrated that HMGB1 directs Th17 sk...

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Detalles Bibliográficos
Autores principales: Zhang, Fang, Su, Xin, Huang, Gang, Xin, Xiao-Feng, Cao, E-Hong, Shi, Yi, Song, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5660212/
https://www.ncbi.nlm.nih.gov/pubmed/29079726
http://dx.doi.org/10.1038/s41598-017-14667-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5660212/
https://www.ncbi.nlm.nih.gov/pubmed/29079726
http://dx.doi.org/10.1038/s41598-017-14667-4

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