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Promoter DNA methylation analysis reveals a novel diagnostic CpG-based biomarker and RAB25 hypermethylation in clear cell renel cell carcinoma

Clear-cell renal cell carcinoma (ccRCC) is a common aggressive urinary malignant tumor that cannot be easily diagnosed at an early stage. The DNA methylation occurs within promoter before precancerous lesion plays a pivotal role that could help us in diagnosing and understanding ccRCC. In this study...

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Detalles Bibliográficos
Autores principales: Gu, Yinmin, Zou, Yi Ming, Lei, Danqing, Huang, Yuanjie, Li, Weidong, Mo, Zengnan, Hu, Yanling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5660223/
https://www.ncbi.nlm.nih.gov/pubmed/29079774
http://dx.doi.org/10.1038/s41598-017-14314-y