Cargando…

Promoter DNA methylation analysis reveals a novel diagnostic CpG-based biomarker and RAB25 hypermethylation in clear cell renel cell carcinoma

Clear-cell renal cell carcinoma (ccRCC) is a common aggressive urinary malignant tumor that cannot be easily diagnosed at an early stage. The DNA methylation occurs within promoter before precancerous lesion plays a pivotal role that could help us in diagnosing and understanding ccRCC. In this study...

Descripción completa

Detalles Bibliográficos
Autores principales:	Gu, Yinmin, Zou, Yi Ming, Lei, Danqing, Huang, Yuanjie, Li, Weidong, Mo, Zengnan, Hu, Yanling
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5660223/ https://www.ncbi.nlm.nih.gov/pubmed/29079774 http://dx.doi.org/10.1038/s41598-017-14314-y

Ejemplares similares

Promoter DNA methylation analysis reveals a combined diagnosis of CpG-based biomarker for prostate cancer
por: Tang, Yuanyuan, et al.
Publicado: (2017)

Functional analysis implicating the SNP rs61552325 in ERBB2 as an effector for androgen-insensitive prostate cancer cell invasion
por: Xin, Xianxiang, et al.
Publicado: (2017)

CpG island hypermethylation go circular (RNA)
por: Dragomir, Mihnea P., et al.
Publicado: (2018)

Aberrant CpG Islands Hypermethylation Profiles in Malignant Gliomas
por: Kim, Kwang Ryeol, et al.
Publicado: (2014)

A reinvestigation of somatic hypermethylation at the PTEN CpG island in cancer cell lines
por: Hesson, Luke B, et al.
Publicado: (2012)

Genomic insights into cancer-associated aberrant CpG island hypermethylation
por: Sproul, Duncan, et al.
Publicado: (2013)

CpG Island Hypermethylation in Gastric Carcinoma and Its Premalignant Lesions
por: Kang, Gyeong Hoon
Publicado: (2012)

Frequent hypermethylation of orphan CpG islands with enhancer activity in cancer
por: Bae, Min Gyun, et al.
Publicado: (2016)

Partially methylated domains are hypervariable in breast cancer and fuel widespread CpG island hypermethylation
por: Brinkman, Arie B., et al.
Publicado: (2019)

Cancer Detection and Classification by CpG Island Hypermethylation Signatures in Plasma Cell-Free DNA
por: Huang, Jinyong, et al.
Publicado: (2021)

Single-CpG-resolution methylome analysis identifies clinicopathologically aggressive CpG island methylator phenotype clear cell renal cell carcinomas
por: Arai, Eri, et al.
Publicado: (2012)

Identifying hypermethylated CpG islands using a quantile regression model
por: Sun, Shuying, et al.
Publicado: (2011)

Circular RNA CpG island hypermethylation-associated silencing in human cancer
por: Ferreira, Humberto J., et al.
Publicado: (2018)

A CpG island hypermethylation profile of primary colorectal carcinomas and colon cancer cell lines
por: Lind, Guro E, et al.
Publicado: (2004)

Detection of promoter hypermethylation of the CpG island of E-cadherin in gastric cardiac adenocarcinoma
por: Guo, W, et al.
Publicado: (2009)

Tissue of origin determines cancer-associated CpG island promoter hypermethylation patterns
por: Sproul, Duncan, et al.
Publicado: (2012)

CpG island hypermethylation-associated silencing of small nucleolar RNAs in human cancer
por: Ferreira, Humberto J., et al.
Publicado: (2012)

Effect of DNMT3A polymorphisms on CpG island hypermethylation in gastric mucosa
por: Takano, Hikaru, et al.
Publicado: (2020)

Enrichment of CpG island shore region hypermethylation in epigenetic breast field cancerization
por: Muse, Meghan E., et al.
Publicado: (2020)

The Role of H3K4 Trimethylation in CpG Islands Hypermethylation in Cancer
por: Zardo, Giuseppe
Publicado: (2021)

A CpG-methylation-based assay to predict survival in clear cell renal cell carcinoma
por: Wei, Jin-Huan, et al.
Publicado: (2015)

Hypermethylation of CpG islands in the mouse asparagine synthetase gene: relationship to asparaginase sensitivity in lymphoma cells. Partial methylation in normal cells
por: Peng, H, et al.
Publicado: (2001)

GATA5 CpG island hypermethylation is an independent predictor for poor clinical outcome in renal cell carcinoma
por: PETERS, INGA, et al.
Publicado: (2014)

Genome-scale detection of hypermethylated CpG islands in circulating cell-free DNA of hepatocellular carcinoma patients
por: Wen, Lu, et al.
Publicado: (2015)

Loss of EphA7 Expression in Basal Cell Carcinoma by Hypermethylation of CpG Islands in the Promoter Region
por: Liu, Jie, et al.
Publicado: (2022)

Discovery of Novel Hypermethylated Genes in Prostate Cancer Using Genomic CpG Island Microarrays
por: Kron, Ken, et al.
Publicado: (2009)

Hypermethylation of the DLC1 CpG island does not alter gene expression in canine lymphoma
por: Bryan, Jeffrey N, et al.
Publicado: (2009)

CpG island hypermethylation-associated silencing of microRNAs promotes human endometrial cancer
por: Li, Bi-Lan, et al.
Publicado: (2013)

CRMP4 CpG Hypermethylation Predicts Upgrading to Gleason Score ≥ 8 in Prostate Cancer
por: Qin, Xiao-Ping, et al.
Publicado: (2022)

Identification of novel hypermethylated or hypomethylated CpG sites and genes associated with anthracycline-induced cardiomyopathy
por: Singh, Purnima, et al.
Publicado: (2023)

BARX2 expression is downregulated by CpG island hypermethylation and is associated with suppressed cell proliferation and invasion of gastric cancer cells
por: Ma, Juan, et al.
Publicado: (2020)

Preservation of methylated CpG dinucleotides in human CpG islands
por: Panchin, Alexander Y., et al.
Publicado: (2016)

Inactivation of O(6)-methylguanine-DNA methyltransferase by promoter CpG island hypermethylation in gastric cancers
por: Bae, S I, et al.
Publicado: (2002)

RASSF2, a potential tumour suppressor, is silenced by CpG island hypermethylation in gastric cancer
por: Endoh, M, et al.
Publicado: (2005)

Identification of DNA hypermethylation of SOX9 in association with bladder cancer progression using CpG microarrays
por: Aleman, A, et al.
Publicado: (2008)

Transcriptional silencing of the Dickkopfs-3 (Dkk-3) gene by CpG hypermethylation in acute lymphoblastic leukaemia
por: Roman-Gomez, J, et al.
Publicado: (2004)

Hypermethylation of gene body CpG islands predicts high dosage of functional oncogenes in liver cancer
por: Arechederra, Maria, et al.
Publicado: (2018)

A Pilot Study of Aberrant CpG Island Hypermethylation of SPRED1 in Acute Myeloloid Leukemia
por: Sun, Jingwen, et al.
Publicado: (2019)

Association of IFN-γ +874 A/T SNP and hypermethylation of the -53 CpG site with tuberculosis susceptibility
por: Álvarez, Guadalupe Inés, et al.
Publicado: (2023)

Mitochondrial GpC and CpG DNA Hypermethylation Cause Metabolic Stress-Induced Mitophagy and Cholestophagy
por: Theys, Claudia, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_bemog247vhb1irptq6ir8vt14l