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Assessment and Translation of the Antibody-in-Lymphocyte Supernatant (ALS) Assay to Improve the Diagnosis of Enteric Fever in Two Controlled Human Infection Models and an Endemic Area of Nepal

New diagnostic tests for enteric fever are urgently needed to assist with timely antimicrobial treatment of patients and to measure the efficacy of prevention measures such as vaccination. In a novel translational approach, here we use two recently developed controlled human infection models (CHIM)...

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Detalles Bibliográficos
Autores principales: Darton, Thomas C., Jones, Claire, Dongol, Sabina, Voysey, Merryn, Blohmke, Christoph J., Shrestha, Rajendra, Karkey, Abhilasha, Shakya, Mila, Arjyal, Amit, Waddington, Claire S., Gibani, Malick, Carter, Michael J., Basnyat, Buddha, Baker, Stephen, Pollard, Andrew J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5660281/
https://www.ncbi.nlm.nih.gov/pubmed/29109704
http://dx.doi.org/10.3389/fmicb.2017.02031