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T Follicular Helper Cells and B Cell Dysfunction in Aging and HIV-1 Infection

T follicular helper (Tfh) cells are a subset of CD4 T cells that provide critical signals to antigen-primed B cells in germinal centers to undergo proliferation, isotype switching, and somatic hypermutation to generate long-lived plasma cells and memory B cells during an immune response. The quantit...

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Detalles Bibliográficos
Autores principales: Pallikkuth, Suresh, de Armas, Lesley, Rinaldi, Stefano, Pahwa, Savita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5660291/
https://www.ncbi.nlm.nih.gov/pubmed/29109730
http://dx.doi.org/10.3389/fimmu.2017.01380