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Single-virion sequencing of lamivudine-treated HBV populations reveal population evolution dynamics and demographic history

BACKGROUND: Viral populations are complex, dynamic, and fast evolving. The evolution of groups of closely related viruses in a competitive environment is termed quasispecies. To fully understand the role that quasispecies play in viral evolution, characterizing the trajectories of viral genotypes in...

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Detalles Bibliográficos
Autores principales: Zhu, Yuan O., Aw, Pauline P. K., de Sessions, Paola Florez, Hong, Shuzhen, See, Lee Xian, Hong, Lewis Z., Wilm, Andreas, Li, Chen Hao, Hue, Stephane, Lim, Seng Gee, Nagarajan, Niranjan, Burkholder, William F., Hibberd, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5660452/
https://www.ncbi.nlm.nih.gov/pubmed/29078745
http://dx.doi.org/10.1186/s12864-017-4217-1