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Dynamic changes in eIF4F-mRNA interactions revealed by global analyses of environmental stress responses

BACKGROUND: Translation factors eIF4E and eIF4G form eIF4F, which interacts with the messenger RNA (mRNA) 5′ cap to promote ribosome recruitment and translation initiation. Variations in the association of eIF4F with individual mRNAs likely contribute to differences in translation initiation frequen...

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Detalles Bibliográficos
Autores principales: Costello, Joseph L., Kershaw, Christopher J., Castelli, Lydia M., Talavera, David, Rowe, William, Sims, Paul F. G., Ashe, Mark P., Grant, Christopher M., Hubbard, Simon J., Pavitt, Graham D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5660459/
https://www.ncbi.nlm.nih.gov/pubmed/29078784
http://dx.doi.org/10.1186/s13059-017-1338-4