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Dynamic changes in eIF4F-mRNA interactions revealed by global analyses of environmental stress responses
BACKGROUND: Translation factors eIF4E and eIF4G form eIF4F, which interacts with the messenger RNA (mRNA) 5′ cap to promote ribosome recruitment and translation initiation. Variations in the association of eIF4F with individual mRNAs likely contribute to differences in translation initiation frequen...
Autores principales: | Costello, Joseph L., Kershaw, Christopher J., Castelli, Lydia M., Talavera, David, Rowe, William, Sims, Paul F. G., Ashe, Mark P., Grant, Christopher M., Hubbard, Simon J., Pavitt, Graham D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5660459/ https://www.ncbi.nlm.nih.gov/pubmed/29078784 http://dx.doi.org/10.1186/s13059-017-1338-4 |
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