HLA-B*14:02-Restricted Env-Specific CD8(+) T-Cell Activity Has Highly Potent Antiviral Efficacy Associated with Immune Control of HIV Infection

Immune control of human immunodeficiency virus type 1 (HIV) infection is typically associated with effective Gag-specific CD8(+) T-cell responses. We here focus on HLA-B*14, which protects against HIV disease progression, but the immunodominant HLA-B*14-restricted anti-HIV response is Env specific (...

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Detalles Bibliográficos
Autores principales: Leitman, Ellen M., Willberg, Christian B., Tsai, Ming-Han, Chen, Huabiao, Buus, Søren, Chen, Fabian, Riddell, Lynn, Haas, David, Fellay, Jacques, Goedert, James J., Piechocka-Trocha, Alicja, Walker, Bruce D., Martin, Jeffrey, Deeks, Steven, Wolinsky, Steven M., Martinson, Jeremy, Martin, Maureen, Qi, Ying, Sáez-Cirión, Asier, Yang, Otto O., Matthews, Philippa C., Carrington, Mary, Goulder, Philip J. R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2017
Materias:
Pathogenesis and Immunity
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5660483/
https://www.ncbi.nlm.nih.gov/pubmed/28878089
http://dx.doi.org/10.1128/JVI.00544-17

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5660483/
https://www.ncbi.nlm.nih.gov/pubmed/28878089
http://dx.doi.org/10.1128/JVI.00544-17

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