Inherited Chromosomally Integrated Human Herpesvirus 6 Genomes Are Ancient, Intact, and Potentially Able To Reactivate from Telomeres

The genomes of human herpesvirus 6A (HHV-6A) and HHV-6B have the capacity to integrate into telomeres, the essential capping structures of chromosomes that play roles in cancer and ageing. About 1% of people worldwide are carriers of chromosomally integrated HHV-6 (ciHHV-6), which is inherited as a...

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Detalles Bibliográficos
Autores principales: Zhang, Enjie, Bell, Adam J., Wilkie, Gavin S., Suárez, Nicolás M., Batini, Chiara, Veal, Colin D., Armendáriz-Castillo, Isaac, Neumann, Rita, Cotton, Victoria E., Huang, Yan, Porteous, David J., Jarrett, Ruth F., Davison, Andrew J., Royle, Nicola J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2017
Materias:
Genetic Diversity and Evolution
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5660504/
https://www.ncbi.nlm.nih.gov/pubmed/28835501
http://dx.doi.org/10.1128/JVI.01137-17

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5660504/
https://www.ncbi.nlm.nih.gov/pubmed/28835501
http://dx.doi.org/10.1128/JVI.01137-17

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