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A functional genomics predictive network model identifies regulators of inflammatory bowel disease

A major challenge in inflammatory bowel disease (IBD) is the integration of diverse IBD data sets to construct predictive models of IBD. We present a predictive model of the immune component of IBD that informs causal relationships among loci previously linked to IBD through genome-wide association...

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Detalles Bibliográficos
Autores principales: Peters, Lauren A, Perrigoue, Jacqueline, Mortha, Arthur, Iuga, Alina, Song, Won-min, Neiman, Eric M, Llewellyn, Sean R, Di Narzo, Antonio, Kidd, Brian A, Telesco, Shannon E, Zhao, Yongzhong, Stojmirovic, Aleksandar, Sendecki, Jocelyn, Shameer, Khader, Miotto, Riccardo, Losic, Bojan, Shah, Hardik, Lee, Eunjee, Wang, Minghui, Faith, Jeremiah J, Kasarskis, Andrew, Brodmerkel, Carrie, Curran, Mark, Das, Anuk, Friedman, Joshua R, Fukui, Yoshinori, Humphrey, Mary Beth, Iritani, Brian M, Sibinga, Nicholas, Tarrant, Teresa K, Argmann, Carmen, Hao, Ke, Roussos, Panos, Zhu, Jun, Zhang, Bin, Dobrin, Radu, Mayer, Lloyd F, Schadt, Eric E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5660607/
https://www.ncbi.nlm.nih.gov/pubmed/28892060
http://dx.doi.org/10.1038/ng.3947