ATP binding controls distinct structural transitions of Escherichia coli DNA gyrase in complex with DNA

DNA gyrase is a molecular motor that harnesses the free energy of ATP hydrolysis to introduce negative supercoils into DNA. A critical step in this reaction is the formation of a chiral DNA wrap on a similar scale to the nucleosome. Here we observe gyrase structural dynamics using a single-molecule...

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Detalles Bibliográficos
Autores principales: Basu, Aakash, Schoeffler, Allyn J., Berger, James M., Bryant, Zev
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5660678/
https://www.ncbi.nlm.nih.gov/pubmed/22484318
http://dx.doi.org/10.1038/nsmb.2278

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5660678/
https://www.ncbi.nlm.nih.gov/pubmed/22484318
http://dx.doi.org/10.1038/nsmb.2278

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