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Intramuscular DNA Vaccination of Juvenile Carp against Spring Viremia of Carp Virus Induces Full Protection and Establishes a Virus-Specific B and T Cell Response

Although spring viremia of carp virus (SVCV) can cause high mortalities in common carp, a commercial vaccine is not available for worldwide use. Here, we report a DNA vaccine based on the expression of the SVCV glycoprotein (G) which, when injected in the muscle even at a single low dose of 0.1 µg D...

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Detalles Bibliográficos
Autores principales: Embregts, Carmen W. E., Rigaudeau, Dimitri, Veselý, Tomáš, Pokorová, Dagmar, Lorenzen, Niels, Petit, Jules, Houel, Armel, Dauber, Malte, Schütze, Heike, Boudinot, Pierre, Wiegertjes, Geert F., Forlenza, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5660689/
https://www.ncbi.nlm.nih.gov/pubmed/29114248
http://dx.doi.org/10.3389/fimmu.2017.01340