Crosstalk between Receptor and Non-receptor Mediated Chemical Modes of Action in Rat Livers Converges through a Dysregulated Gene Expression Network at Tumor Suppressor Tp53

Chemicals, toxicants, and environmental stressors mediate their biologic effect through specific modes of action (MOAs). These encompass key molecular events that lead to changes in the expression of genes within regulatory pathways. Elucidating shared biologic processes and overlapping gene network...

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Detalles Bibliográficos
Autores principales: Funderburk, Karen M., Auerbach, Scott S., Bushel, Pierre R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5660693/
https://www.ncbi.nlm.nih.gov/pubmed/29114260
http://dx.doi.org/10.3389/fgene.2017.00157

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5660693/
https://www.ncbi.nlm.nih.gov/pubmed/29114260
http://dx.doi.org/10.3389/fgene.2017.00157

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