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Entanglement of UPR(ER) in Aging Driven Neurodegenerative Diseases
The endoplasmic reticulum (ER) is an indispensable cellular organelle that remains highly active in neuronal cells. The ER bears the load of maintaining protein homeostasis in the cellular network by managing the folding of incoming nascent peptides; however, the stress imposed by physiological/envi...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5660724/ https://www.ncbi.nlm.nih.gov/pubmed/29114219 http://dx.doi.org/10.3389/fnagi.2017.00341 |