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Entanglement of UPR(ER) in Aging Driven Neurodegenerative Diseases

The endoplasmic reticulum (ER) is an indispensable cellular organelle that remains highly active in neuronal cells. The ER bears the load of maintaining protein homeostasis in the cellular network by managing the folding of incoming nascent peptides; however, the stress imposed by physiological/envi...

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Detalles Bibliográficos
Autores principales: Rahman, Safikur, Jan, Arif Tasleem, Ayyagari, Archana, Kim, Jiwoo, Kim, Jihoe, Minakshi, Rinki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5660724/
https://www.ncbi.nlm.nih.gov/pubmed/29114219
http://dx.doi.org/10.3389/fnagi.2017.00341