Patients Affected by Unmethylated O(6)-Methylguanine-DNA Methyltransferase Glioblastoma Undergoing Radiochemotherapy May Benefit from Moderately Dose-Escalated Radiotherapy

PURPOSE: To compare the therapeutic results of two radiotherapy (RT) dose schedules in combined temozolomide- (TMZ-) RT treatment in newly diagnosed glioblastoma (GB), according to the O(6)-methylguanine-DNA methyltransferase (MGMT) methylation status. MATERIAL AND METHOD: Patients received either s...

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Detalles Bibliográficos
Autores principales: Tini, Paolo, Nardone, Valerio, Pastina, Pierpaolo, Battaglia, Giuseppe, Miracco, Clelia, Sebaste, Lucio, Rubino, Giovanni, Cerase, Alfonso, Pirtoli, Luigi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5660746/
https://www.ncbi.nlm.nih.gov/pubmed/29159183
http://dx.doi.org/10.1155/2017/9461402

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5660746/
https://www.ncbi.nlm.nih.gov/pubmed/29159183
http://dx.doi.org/10.1155/2017/9461402

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