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Patients Affected by Unmethylated O(6)-Methylguanine-DNA Methyltransferase Glioblastoma Undergoing Radiochemotherapy May Benefit from Moderately Dose-Escalated Radiotherapy
PURPOSE: To compare the therapeutic results of two radiotherapy (RT) dose schedules in combined temozolomide- (TMZ-) RT treatment in newly diagnosed glioblastoma (GB), according to the O(6)-methylguanine-DNA methyltransferase (MGMT) methylation status. MATERIAL AND METHOD: Patients received either s...
Autores principales: | Tini, Paolo, Nardone, Valerio, Pastina, Pierpaolo, Battaglia, Giuseppe, Miracco, Clelia, Sebaste, Lucio, Rubino, Giovanni, Cerase, Alfonso, Pirtoli, Luigi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5660746/ https://www.ncbi.nlm.nih.gov/pubmed/29159183 http://dx.doi.org/10.1155/2017/9461402 |
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