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The Role of Costimulation Blockade in Solid Organ and Islet Xenotransplantation

Pig-to-human xenotransplantation offers a potential bridge to the growing disparity between patients with end-stage organ failure and graft availability. Early studies attempting to overcome cross-species barriers demonstrated robust humoral immune responses to discordant xenoantigens. Recent advanc...

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Detalles Bibliográficos
Autores principales: Samy, Kannan P., Butler, James R., Li, Ping, Cooper, David K. C., Ekser, Burcin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5660816/
https://www.ncbi.nlm.nih.gov/pubmed/29159187
http://dx.doi.org/10.1155/2017/8415205