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The effects of intranasal esketamine (84 mg) and oral mirtazapine (30 mg) on on-road driving performance: a double-blind, placebo-controlled study

RATIONALE: The purpose of this study is to evaluate the single dose effect of intranasal esketamine (84 mg) compared to placebo on on-road driving performance. Mirtazapine (oral, 30 mg) was used as a positive control, as this antidepressant drug is known to negatively affect driving performance. MET...

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Detalles Bibliográficos
Autores principales: van de Loo, Aurora J. A. E., Bervoets, Adriana C., Mooren, Loes, Bouwmeester, Noor H., Garssen, Johan, Zuiker, Rob, van Amerongen, Guido, van Gerven, Joop, Singh, Jaskaran, der Ark, Peter Van, Fedgchin, Maggie, Morrison, Randall, Wajs, Ewa, Verster, Joris C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5660834/
https://www.ncbi.nlm.nih.gov/pubmed/28755104
http://dx.doi.org/10.1007/s00213-017-4706-6