Effects of methotrexate exposure on medaka (Oryzias latipes) testes

For the purpose of clarifying the histopathological effects of methotrexate (MTX) on medaka testes, wild-type and homogenic p53-deficient male medaka at 4 to 6 months post-hatching were exposed to 0.25 mg/ml of MTX for 96 h with histopathological examination of testes at 24, 48, 72 and 96 h. At 72 a...

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Detalles Bibliográficos
Autores principales: Hirako, Ayano, Takeoka, Yuki, Furukawa, Satoshi, Sugiyama, Akihiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Japanese Society of Toxicologic Pathology 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5660950/
https://www.ncbi.nlm.nih.gov/pubmed/29097838
http://dx.doi.org/10.1293/tox.2017-0029

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5660950/
https://www.ncbi.nlm.nih.gov/pubmed/29097838
http://dx.doi.org/10.1293/tox.2017-0029

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