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Effects of methotrexate exposure on medaka (Oryzias latipes) testes
For the purpose of clarifying the histopathological effects of methotrexate (MTX) on medaka testes, wild-type and homogenic p53-deficient male medaka at 4 to 6 months post-hatching were exposed to 0.25 mg/ml of MTX for 96 h with histopathological examination of testes at 24, 48, 72 and 96 h. At 72 a...
Autores principales: | Hirako, Ayano, Takeoka, Yuki, Furukawa, Satoshi, Sugiyama, Akihiko |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Japanese Society of Toxicologic Pathology
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5660950/ https://www.ncbi.nlm.nih.gov/pubmed/29097838 http://dx.doi.org/10.1293/tox.2017-0029 |
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