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Structure-based insights into self-cleavage by a four-way junctional twister-sister ribozyme
Here we report on the crystal structure and cleavage assays of a four-way junctional twister-sister self-cleaving ribozyme. Notably, 11 conserved spatially separated loop nucleotides are brought into close proximity at the ribozyme core through long-range interactions mediated by hydrated Mg(2+) cat...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5660989/ https://www.ncbi.nlm.nih.gov/pubmed/29081514 http://dx.doi.org/10.1038/s41467-017-01276-y |