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Using an NMR metabolomics approach to investigate the pathogenicity of amyloid-beta and alpha-synuclein

INTRODUCTION: The pathogenicity at differing points along the aggregation pathway of many fibril-forming proteins associated with neurodegenerative diseases is unclear. Understanding the effect of different aggregation states of these proteins on cellular processes is essential to enhance understand...

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Detalles Bibliográficos
Autores principales: Phelan, M. M., Caamaño-Gutiérrez, E., Gant, M. S., Grosman, R. X., Madine, J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5661010/
https://www.ncbi.nlm.nih.gov/pubmed/29142509
http://dx.doi.org/10.1007/s11306-017-1289-5