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Potential Anticancer Mechanisms of a Novel EGFR/DNA-Targeting Combi-Molecule (JDF12) against DU145 Prostate Cancer Cells: An iTRAQ-Based Proteomic Analysis

The development of multitargeting drugs is an emerging trend in cancer research. To promote further development and clinical application of multitargeting drugs, this research was performed. MTT assay and flow cytometry of Annexin V/propidium iodide staining were used to confirm the proapoptotic eff...

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Detalles Bibliográficos
Autores principales: Zheng, Haofeng, Liang, Guancan, Chen, Yanxiong, Lin, Sijie, Liu, Wei, Fang, Youqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5661095/
https://www.ncbi.nlm.nih.gov/pubmed/29164150
http://dx.doi.org/10.1155/2017/8050313