Nintedanib reduces ventilation‐augmented bleomycin‐induced epithelial–mesenchymal transition and lung fibrosis through suppression of the Src pathway

Mechanical ventilation (MV) used in patients with acute respiratory distress syndrome (ARDS) can increase lung inflammation and pulmonary fibrogenesis. Src is crucial in mediating the transforming growth factor (TGF)‐β1‐induced epithelial–mesenchymal transition (EMT) during the fibroproliferative ph...

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Detalles Bibliográficos
Autores principales: Li, Li‐Fu, Kao, Kuo‐Chin, Liu, Yung‐Yang, Lin, Chang‐Wei, Chen, Ning‐Hung, Lee, Chung‐Shu, Wang, Chih‐Wei, Yang, Cheng‐Ta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5661114/
https://www.ncbi.nlm.nih.gov/pubmed/28598023
http://dx.doi.org/10.1111/jcmm.13206

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5661114/
https://www.ncbi.nlm.nih.gov/pubmed/28598023
http://dx.doi.org/10.1111/jcmm.13206

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