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Nintedanib reduces ventilation‐augmented bleomycin‐induced epithelial–mesenchymal transition and lung fibrosis through suppression of the Src pathway
Mechanical ventilation (MV) used in patients with acute respiratory distress syndrome (ARDS) can increase lung inflammation and pulmonary fibrogenesis. Src is crucial in mediating the transforming growth factor (TGF)‐β1‐induced epithelial–mesenchymal transition (EMT) during the fibroproliferative ph...
Autores principales: | Li, Li‐Fu, Kao, Kuo‐Chin, Liu, Yung‐Yang, Lin, Chang‐Wei, Chen, Ning‐Hung, Lee, Chung‐Shu, Wang, Chih‐Wei, Yang, Cheng‐Ta |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5661114/ https://www.ncbi.nlm.nih.gov/pubmed/28598023 http://dx.doi.org/10.1111/jcmm.13206 |
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