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Methylglyoxal‐induced apoptosis is dependent on the suppression of c‐FLIP(L) expression via down‐regulation of p65 in endothelial cells
Methylglyoxal (MGO) is a reactive dicarbonyl metabolite of glucose, and its plasma levels are elevated in patients with diabetes. Studies have shown that MGO combines with the amino and sulphhydryl groups of proteins to form stable advanced glycation end products (AGEs), which are associated with va...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5661116/ https://www.ncbi.nlm.nih.gov/pubmed/28444875 http://dx.doi.org/10.1111/jcmm.13188 |