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Oncostatin M induces RIG‐I and MDA5 expression and enhances the double‐stranded RNA response in fibroblasts

Interleukin (IL)‐6‐type cytokines have no direct antiviral activity; nevertheless, they display immune‐modulatory functions. Oncostatin M (OSM), a member of the IL‐6 family, has recently been shown to induce a distinct number of classical interferon stimulated genes (ISG). Most of them are involved...

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Detalles Bibliográficos
Autores principales: Hergovits, Sabine, Mais, Christine, Haan, Claude, Costa‐Pereira, Ana P., Hermanns, Heike M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5661242/
https://www.ncbi.nlm.nih.gov/pubmed/28560754
http://dx.doi.org/10.1111/jcmm.13221