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The EF‐1α promoter maintains high‐level transgene expression from episomal vectors in transfected CHO‐K1 cells

In our previous study, we demonstrated that episomal vectors based on the characteristic sequence of matrix attachment regions (MARs) and containing the cytomegalovirus (CMV) promoter allow transgenes to be maintained episomally in Chinese hamster ovary (CHO) cells. However, the transgene expression...

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Detalles Bibliográficos
Autores principales: Wang, Xiaoyin, Xu, Zhongjie, Tian, Zhengwei, Zhang, Xi, Xu, Danhua, Li, Qin, Zhang, Junhe, Wang, Tianyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5661254/
https://www.ncbi.nlm.nih.gov/pubmed/28557288
http://dx.doi.org/10.1111/jcmm.13216