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miR-214 targets the PTEN-mediated PI3K/Akt signaling pathway and regulates cell proliferation and apoptosis in ovarian cancer

The present study aimed to investigate the potential role of microRNA (miR)-214 in targeting the phosphatase and tensin homolog (PTEN)-mediated phosphoinositide 3-kinase (PI3K)/Akt signaling pathway in ovarian cancer (OC). The target gene of miR-214 was determined by luciferase reporter gene assay a...

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Detalles Bibliográficos
Autores principales: Liu, Jing, Chen, Weiyan, Zhang, Haiyan, Liu, Ting, Zhao, Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5661372/
https://www.ncbi.nlm.nih.gov/pubmed/29113199
http://dx.doi.org/10.3892/ol.2017.6953