Squamous cell transformation and EGFR T790M mutation as acquired resistance mechanisms in a patient with lung adenocarcinoma treated with a tyrosine kinase inhibitor: A case report

The present case report describes the infrequent coexistence of squamous cell transformation and the epidermal growth factor receptor (EGFR) T790M mutation as resistance mechanisms to first line treatment with tyrosine kinase inhibitors. The patient was a 44-year-old female, diagnosed with a primiti...

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Detalles Bibliográficos
Autores principales: Bruno, Rossella, Proietti, Agnese, Alì, Greta, Puppo, Gianfranco, Ribechini, Alessandro, Chella, Antonio, Fontanini, Gabriella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5661389/
https://www.ncbi.nlm.nih.gov/pubmed/29113230
http://dx.doi.org/10.3892/ol.2017.6913

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5661389/
https://www.ncbi.nlm.nih.gov/pubmed/29113230
http://dx.doi.org/10.3892/ol.2017.6913

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