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Development of β-cyclodextrin-based hydrogel microparticles for solubility enhancement of rosuvastatin: an in vitro and in vivo evaluation

The aim of this study was to enhance the solubility of rosuvastatin (RST) calcium by developing β-cyclodextrin-g-poly(2-acrylamido-2-methylpropane sulfonic acid [AMPS]) hydrogel microparticles through aqueous free-radical polymerization technique. Prepared hydrogel microparticles were characterized...

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Detalles Bibliográficos
Autores principales: Sarfraz, Rai Muhammad, Ahmad, Mahmood, Mahmood, Asif, Akram, Muhammad Rouf, Abrar, Asad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5661467/
https://www.ncbi.nlm.nih.gov/pubmed/29123380
http://dx.doi.org/10.2147/DDDT.S143712