Cargando…

Development of β-cyclodextrin-based hydrogel microparticles for solubility enhancement of rosuvastatin: an in vitro and in vivo evaluation

The aim of this study was to enhance the solubility of rosuvastatin (RST) calcium by developing β-cyclodextrin-g-poly(2-acrylamido-2-methylpropane sulfonic acid [AMPS]) hydrogel microparticles through aqueous free-radical polymerization technique. Prepared hydrogel microparticles were characterized...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sarfraz, Rai Muhammad, Ahmad, Mahmood, Mahmood, Asif, Akram, Muhammad Rouf, Abrar, Asad
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2017
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5661467/ https://www.ncbi.nlm.nih.gov/pubmed/29123380 http://dx.doi.org/10.2147/DDDT.S143712

Ejemplares similares

Formulation design and development of matrix diffusion controlled transdermal drug delivery of glimepiride
por: Akram, Muhammad Rouf, et al.
Publicado: (2018)

Development and in vitro evaluation of (β-cyclodextrin-g-methacrylic acid)/Na(+)-montmorillonite nanocomposite hydrogels for controlled delivery of lovastatin
por: Mahmood, Asif, et al.
Publicado: (2019)

Orally Administered, Biodegradable and Biocompatible Hydroxypropyl–β–Cyclodextrin Grafted Poly(methacrylic acid) Hydrogel for pH Sensitive Sustained Anticancer Drug Delivery
por: Batool, Nighat, et al.
Publicado: (2022)

Development and Optimization of Tamarind Gum-β-Cyclodextrin-g-Poly(Methacrylate) pH-Responsive Hydrogels for Sustained Delivery of Acyclovir
por: Shafiq, Kanza, et al.
Publicado: (2022)

Development of Tofacitinib Loaded pH-Responsive Chitosan/Mucin Based Hydrogel Microparticles: In-Vitro Characterization and Toxicological Screening
por: Malatani, Rania T., et al.
Publicado: (2023)

Development of β-cyclodextrin/polyvinypyrrolidone-co-poly (2-acrylamide-2-methylpropane sulphonic acid) hybrid nanogels as nano-drug delivery carriers to enhance the solubility of Rosuvastatin: An in vitro and in vivo evaluation
por: Shoukat, Hina, et al.
Publicado: (2022)

Cross-linked β-cyclodextrin and carboxymethyl cellulose hydrogels for controlled drug delivery of acyclovir
por: Malik, Nadia Shamshad, et al.
Publicado: (2017)

Novel Black Seed Polysaccharide Extract-g-Poly (Acrylate) pH-Responsive Hydrogel Nanocomposites for Safe Oral Insulin Delivery: Development, In Vitro, In Vivo and Toxicological Evaluation
por: Shabir, Farya, et al.
Publicado: (2022)

β-cyclodextrin chitosan-based hydrogels with tunable pH-responsive properties for controlled release of acyclovir: design, characterization, safety, and pharmacokinetic evaluation
por: Malik, Nadia Shamshad, et al.
Publicado: (2021)

pH Responsive Hydrogels for the Delivery of Capecitabine: Development, Optimization and Pharmacokinetic Studies
por: Rehman, Umaira, et al.
Publicado: (2022)

Development and Evaluation of Cellulose Derivative and Pectin Based Swellable pH Responsive Hydrogel Network for Controlled Delivery of Cytarabine
por: Batool, Nighat, et al.
Publicado: (2023)

Synthesis and Characterization of Carboxymethyl Chitosan Nanosponges with Cyclodextrin Blends for Drug Solubility Improvement
por: Rizvi, Syeda Sadia Batool, et al.
Publicado: (2022)

Voriconazole Cyclodextrin Based Polymeric Nanobeads for Enhanced Solubility and Activity: In Vitro/In Vivo and Molecular Simulation Approach
por: Farooq, Mudassir, et al.
Publicado: (2023)

Formulation, Characterization, and In Vitro Drug Release Study of β-Cyclodextrin-Based Smart Hydrogels
por: Suhail, Muhammad, et al.
Publicado: (2022)

In Vitro and Ex Vivo Evaluation of Nepafenac-Based Cyclodextrin Microparticles for Treatment of Eye Inflammation
por: Lorenzo-Veiga, Blanca, et al.
Publicado: (2020)

Simvastatin Loaded Dissolvable Microneedle Patches with Improved Pharmacokinetic Performance
por: , Zulcaif, et al.
Publicado: (2022)

Statistically Optimized Polymeric Buccal Films of Eletriptan Hydrobromide and Itopride Hydrochloride: An In Vivo Pharmacokinetic Study
por: Safhi, Awaji Y., et al.
Publicado: (2023)

Effect of hydroxylpropyl-β-cyclodextrin on Solubility of Carvedilol
por: Shewale, B. D., et al.
Publicado: (2008)

Solubility of Cyclodextrins and Drug/Cyclodextrin Complexes
por: Saokham, Phennapha, et al.
Publicado: (2018)

Gallic acid/hydroxypropyl-β-cyclodextrin complex: Improving solubility for application on in vitro/ in vivo Candida albicans biofilms
por: Teodoro, Guilherme Rodrigues, et al.
Publicado: (2017)

Press-Coated Aceclofenac Tablets for Pulsatile Drug Delivery: Formulation and In Vitro Evaluations
por: Rashid, Rizwana, et al.
Publicado: (2022)

Differential Diabetogenic Effect of Pitavastatin and Rosuvastatin, in vitro and in vivo
por: Cho, Yongin, et al.
Publicado: (2020)

Effect of β-Cyclodextrin Complexation on Solubility and Enzymatic Conversion of Naringin
por: Cui, Li, et al.
Publicado: (2012)

Release of β-galactosidase from poloxamine/α-cyclodextrin hydrogels
por: Estévez, César A, et al.
Publicado: (2014)

β-Cyclodextrin Modified Hydrogels of Kappa-Carrageenan for Methotrexate Delivery
por: Nikitina, Maria, et al.
Publicado: (2023)

In Vitro and In Vivo Evaluation of Oxatomide β-Cyclodextrin Inclusion Complex
por: Hashem, Fahima M., et al.
Publicado: (2013)

In Vitro Enhanced Skin Permeation and Retention of Imiquimod Loaded in β-Cyclodextrin Nanosponge Hydrogel
por: Argenziano, Monica, et al.
Publicado: (2019)

Enhancement of apixaban's solubility and dissolution rate by inclusion complex (β-cyclodextrin and hydroxypropyl β-cyclodextrin) and computational calculation of their inclusion complexes
por: Salman, Zainab N., et al.
Publicado: (2023)

In vivo and In vitro Drug Interactions Study of Glimepride with Atorvastatin and Rosuvastatin
por: Galani, VJ, et al.
Publicado: (2010)

Effect of 2-Hydroxypropyl-β-cyclodextrin on Solubility of Sparingly Soluble Drug Derivatives of Anthranilic Acid
por: Domańska, Urszula, et al.
Publicado: (2011)

Effect of Hydrophilic Polymers on Complexation Efficiency of Cyclodextrins in Enhancing Solubility and Release of Diflunisal
por: Bashir, Mehreen, et al.
Publicado: (2020)

Deep Eutectic Solvents for Efficient Drug Solvation: Optimizing Composition and Ratio for Solubility of β-Cyclodextrin
por: Shumilin, Ilan, et al.
Publicado: (2023)

Effect of β-cyclodextrin complexation on solubility and enzymatic hydrolysis rate of icariin
por: Cui, Li, et al.
Publicado: (2013)

β-Cyclodextrin-Polyacrylamide Hydrogel for Removal of Organic Micropollutants from Water
por: Song, Xia, et al.
Publicado: (2021)

Phylogenetic and 2D/3D Analysis of HCV 1a NS4A Gene/Protein in Pakistani Isolates
por: Hussain, Abrar, et al.
Publicado: (2015)

Preparation of Fluconazole β-Cyclodextrin Complex Ocuserts: In Vitro and In Vivo Evaluation
por: Abdul Ahad, Hindustan, et al.
Publicado: (2011)

Non-ionic thiolated cyclodextrins – the next generation
por: Moghadam, Ali, et al.
Publicado: (2018)

Multilayer-Coated Tablet of Clopidogrel and Rosuvastatin: Preparation and In Vitro/In vivo Characterization
por: Seo, Ki-Soo, et al.
Publicado: (2019)

Development and Characterization of Eudragit(®) EPO-Based Solid Dispersion of Rosuvastatin Calcium to Foresee the Impact on Solubility, Dissolution and Antihyperlipidemic Activity
por: Inam, Sana, et al.
Publicado: (2022)

Synthesis and characterization of a hyper-branched water-soluble β-cyclodextrin polymer
por: Trotta, Francesco, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_n0oepediac8pg5b2lhuo8j54ed