A signature of enhanced lipid metabolism, lipid peroxidation and aldehyde stress in therapy-induced senescence

At their proliferative limit, normal cells arrest and undergo replicative senescence, displaying large cell size, flat morphology, and senescence-associated beta-galactosidase (SA-β-Gal) activity. Normal or tumor cells exposed to genotoxic stress undergo therapy-induced senescence (TIS), displaying...

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Detalles Bibliográficos
Autores principales: Flor, Amy C, Wolfgeher, Don, Wu, Ding, Kron, Stephen J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5661608/
https://www.ncbi.nlm.nih.gov/pubmed/29090099
http://dx.doi.org/10.1038/cddiscovery.2017.75

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5661608/
https://www.ncbi.nlm.nih.gov/pubmed/29090099
http://dx.doi.org/10.1038/cddiscovery.2017.75

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