Cargando…
A signature of enhanced lipid metabolism, lipid peroxidation and aldehyde stress in therapy-induced senescence
At their proliferative limit, normal cells arrest and undergo replicative senescence, displaying large cell size, flat morphology, and senescence-associated beta-galactosidase (SA-β-Gal) activity. Normal or tumor cells exposed to genotoxic stress undergo therapy-induced senescence (TIS), displaying...
| Autores principales: | , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2017
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5661608/ https://www.ncbi.nlm.nih.gov/pubmed/29090099 http://dx.doi.org/10.1038/cddiscovery.2017.75 |