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A novel peptide specifically binding to VEGF receptor suppresses angiogenesis in vitro and in vivo

Vascular endothelial growth factor (VEGF), one of the most important angiogenic factors, plays an essential role in both physiological and pathological angiogenesis through binding to VEGF receptors (VEGFRs). Here we report a novel peptide designated HRHTKQRHTALH (peptide HRH), which was isolated fr...

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Detalles Bibliográficos
Autores principales: Zhang, Yuan, He, Bifang, Liu, Kun, Ning, Lin, Luo, Delun, Xu, Kai, Zhu, Wenli, Wu, Zhigang, Huang, Jian, Xu, Xun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5661615/
https://www.ncbi.nlm.nih.gov/pubmed/29263914
http://dx.doi.org/10.1038/sigtrans.2017.10