Platelets prime hematopoietic–vascular niche to drive angiocrine-mediated liver regeneration

In mammals, the livers regenerate after chemical injury or resection of hepatic lobe by hepatectomy. How liver regeneration is initiated after mass loss remains to be defined. Here we report that following liver injury, activated platelets deploy SDF-1 and VEGF-A to stimulate CXCR7(+) liver sinusoid...

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Detalles Bibliográficos
Autores principales: Shido, Koji, Chavez, Deebly, Cao, Zhongwei, Ko, Jane L, Rafii, Shahin, Ding, Bi-Sen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5661617/
https://www.ncbi.nlm.nih.gov/pubmed/29201496
http://dx.doi.org/10.1038/sigtrans.2016.44

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5661617/
https://www.ncbi.nlm.nih.gov/pubmed/29201496
http://dx.doi.org/10.1038/sigtrans.2016.44

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