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Platelets prime hematopoietic–vascular niche to drive angiocrine-mediated liver regeneration
In mammals, the livers regenerate after chemical injury or resection of hepatic lobe by hepatectomy. How liver regeneration is initiated after mass loss remains to be defined. Here we report that following liver injury, activated platelets deploy SDF-1 and VEGF-A to stimulate CXCR7(+) liver sinusoid...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5661617/ https://www.ncbi.nlm.nih.gov/pubmed/29201496 http://dx.doi.org/10.1038/sigtrans.2016.44 |