Let’s talk about Secs: Sec61, Sec62 and Sec63 in signal transduction, oncology and personalized medicine

The heterotrimeric Sec61 complex and the dimeric Sec62/Sec63 complex are located in the membrane of the human endoplasmic reticulum (ER) and play a central role in translocation of nascent and newly synthesized precursor polypeptides into the ER. This process involves targeting of the precursors to...

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Detalles Bibliográficos
Autores principales: Linxweiler, Maximilian, Schick, Bernhard, Zimmermann, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5661625/
https://www.ncbi.nlm.nih.gov/pubmed/29263911
http://dx.doi.org/10.1038/sigtrans.2017.2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5661625/
https://www.ncbi.nlm.nih.gov/pubmed/29263911
http://dx.doi.org/10.1038/sigtrans.2017.2

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