UV-induced damage to DNA: effect of cytosine methylation on pyrimidine dimerization

Methylation/demethylation of cytosine plays an important role in epigenetic signaling, the reversibility of epigenetic modifications offering important opportunities for targeted therapies. Actually, methylated sites have been correlated with mutational hotspots detected in skin cancers. The present...

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Detalles Bibliográficos
Autores principales: Martinez-Fernandez, Lara, Banyasz, Akos, Esposito, Luciana, Markovitsi, Dimitra, Improta, Roberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Perspective
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5661629/
https://www.ncbi.nlm.nih.gov/pubmed/29263920
http://dx.doi.org/10.1038/sigtrans.2017.21

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5661629/
https://www.ncbi.nlm.nih.gov/pubmed/29263920
http://dx.doi.org/10.1038/sigtrans.2017.21

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