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Targeting cellular pathways in glioblastoma multiforme

Glioblastoma multiforme (GBM) is a debilitating disease that is associated with poor prognosis, short median patient survival and a very limited response to therapies. GBM has a very complex pathogenesis that involves mutations and alterations of several key cellular pathways that are involved in ce...

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Detalles Bibliográficos
Autores principales: Pearson, Joshua R D, Regad, Tarik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5661637/
https://www.ncbi.nlm.nih.gov/pubmed/29263927
http://dx.doi.org/10.1038/sigtrans.2017.40