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Facile Synthesis of a Next Generation Safety‐Catch Acid‐Labile Linker, SCAL‐2, Suitable for Solid‐Phase Synthesis, On‐Support Display and for Post‐Synthesis Tagging

The SCAL linker, a safety catch linker, is amongst the most versatile linkers for solid phase synthesis. It was originally described in 1991 by Pátek and Lebl. Yet, its application has been hindered by the low yields of published synthetic routes. Over time, the exceptional versatility of this linke...

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Detalles Bibliográficos
Autores principales: Portal, Christophe, Hintersteiner, Martin, Barbeau, Olivier, Dodd, Peter, Huggett, Margaret, Pérez‐Pi, Irene, Evans, David, Auer, Manfred
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5661701/
https://www.ncbi.nlm.nih.gov/pubmed/29104911
http://dx.doi.org/10.1002/slct.201701519