Lgr6 is a stem cell marker in mouse skin squamous carcinomas

The G-protein-coupled receptors Lgr4/5/6 are Wnt signalling mediators, but their functions in squamous carcinomas (SCCs) are unclear. Using lineage tracing in Lgr5-EGFP-CreERT2- and Lgr6-EGFP-CreERT2- Rosa26/Tomato reporter mice, we demonstrate that Lgr6, but not Lgr5, acts as an epithelial stem cel...

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Detalles Bibliográficos
Autores principales: Huang, Phillips Y., Kandyba, Eve, Jabouille, Arnaud, Sjolund, Jonas, Kumar, Atul, Halliwill, Kyle, McCreery, Melissa, DelRosario, Reyno, Kang, Hio Chung, Wong, Christine E., Seibler, Jost, Beuger, Vincent, Pellegrino, Maurizio, Sciambi, Adam, Eastburn, Dennis J., Balmain, Allan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5662105/
https://www.ncbi.nlm.nih.gov/pubmed/28945253
http://dx.doi.org/10.1038/ng.3957

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5662105/
https://www.ncbi.nlm.nih.gov/pubmed/28945253
http://dx.doi.org/10.1038/ng.3957

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