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MicroRNA profiling of human primary macrophages exposed to dengue virus identifies miRNA-3614-5p as antiviral and regulator of ADAR1 expression

BACKGROUND: Due to the high burden of dengue disease worldwide, a better understanding of the interactions between dengue virus (DENV) and its human host cells is of the utmost importance. Although microRNAs modulate the outcome of several viral infections, their contribution to DENV replication is...

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Detalles Bibliográficos
Autores principales: Diosa-Toro, Mayra, Echavarría-Consuegra, Liliana, Flipse, Jacky, Fernández, Geysson Javier, Kluiver, Joost, van den Berg, Anke, Urcuqui-Inchima, Silvio, Smit, Jolanda M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5662241/
https://www.ncbi.nlm.nih.gov/pubmed/29045406
http://dx.doi.org/10.1371/journal.pntd.0005981