TIP60 represses telomerase expression by inhibiting Sp1 binding to the TERT promoter

HIV1-TAT interactive protein (TIP60) is a haploinsufficient tumor suppressor. However, the potential mechanisms endowing its tumor suppressor ability remain incompletely understood. It plays a vital role in virus-induced cancers where TIP60 down-regulates the expression of human papillomavirus (HPV)...

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Detalles Bibliográficos
Autores principales: Rajagopalan, Deepa, Pandey, Amit Kumar, Xiuzhen, Magdalene Claire, Lee, Kwok Kin, Hora, Shainan, Zhang, Yanzhou, Chua, Boon Haow, Kwok, Hui Si, Bhatia, Shreshtha Sailesh, Deng, Lih Wen, Tenen, Daniel G., Kappei, Dennis, Jha, Sudhakar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5662243/
https://www.ncbi.nlm.nih.gov/pubmed/29045464
http://dx.doi.org/10.1371/journal.ppat.1006681

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5662243/
https://www.ncbi.nlm.nih.gov/pubmed/29045464
http://dx.doi.org/10.1371/journal.ppat.1006681

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