α5β1-Integrin promotes tension-dependent mammary epithelial cell invasion by engaging the fibronectin synergy site

Tumors are fibrotic and characterized by abundant, remodeled, and cross-linked collagen that stiffens the extracellular matrix stroma. The stiffened collagenous stroma fosters malignant transformation of the tissue by increasing tumor cell tension to promote focal adhesion formation and potentiate g...

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Detalles Bibliográficos
Autores principales: Miroshnikova, Y. A., Rozenberg, G. I., Cassereau, L., Pickup, M., Mouw, J. K., Ou, G., Templeman, K. L., Hannachi, E.-I., Gooch, K. J., Sarang-Sieminski, A. L., García, A. J., Weaver, V. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2017
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5662256/
https://www.ncbi.nlm.nih.gov/pubmed/28877984
http://dx.doi.org/10.1091/mbc.E17-02-0126

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5662256/
https://www.ncbi.nlm.nih.gov/pubmed/28877984
http://dx.doi.org/10.1091/mbc.E17-02-0126

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