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MTBP, the partner of Treslin, contains a novel DNA-binding domain that is essential for proper initiation of DNA replication
Treslin, which is essential for incorporation of Cdc45 into the replicative helicase, possesses a partner called MTBP (Mdm2-binding protein). We have analyzed Xenopus and human MTBP to assess its role in DNA replication. Depletion of MTBP from Xenopus egg extracts, which also removes Treslin, abolis...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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The American Society for Cell Biology
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5662258/ https://www.ncbi.nlm.nih.gov/pubmed/28877985 http://dx.doi.org/10.1091/mbc.E17-07-0448 |