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ADP-ribosylation factor–like 4C binding to filamin-A modulates filopodium formation and cell migration

Changes in cell morphology and the physical forces that occur during migration are generated by a dynamic filamentous actin cytoskeleton. The ADP-ribosylation factor–like 4C (Arl4C) small GTPase acts as a molecular switch to regulate morphological changes and cell migration, although the mechanism b...

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Detalles Bibliográficos
Autores principales: Chiang, Tsai-Shin, Wu, Hsu-Feng, Lee, Fang-Jen S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5662259/
https://www.ncbi.nlm.nih.gov/pubmed/28855378
http://dx.doi.org/10.1091/mbc.E17-01-0059