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Shear stress induces noncanonical autophagy in intestinal epithelial monolayers

Flow of fluids through the gut, such as milk from a neonatal diet, generates a shear stress on the unilaminar epithelium lining the lumen. We report that exposure to physiological levels of fluid shear stress leads to the formation of large vacuoles, containing extracellular contents within polarizi...

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Detalles Bibliográficos
Autores principales: Kim, Sun Wook, Ehrman, Jonathan, Ahn, Mok-Ryeon, Kondo, Jumpei, Lopez, Andrea A. Mancheno, Oh, Yun Sik, Kim, Xander H., Crawley, Scott W., Goldenring, James R., Tyska, Matthew J., Rericha, Erin C., Lau, Ken S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5662261/
https://www.ncbi.nlm.nih.gov/pubmed/28855375
http://dx.doi.org/10.1091/mbc.E17-01-0021